Technology offers
ETH Zurich keeps a portfolio of licensing opportunites. On this page we display a selection of technologies that ETH Zurich filed as patents. For staying up-to-date see also:
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Latest offer
Synthetic hydrogel matrix for collagen imaging on chip
This microfluidic culture mimics early bone development in vitro. The on-chip assembly is accessible to various imaging techniques, which facilitate the monitoring of cell-secreted collagen fibres and diagnosing tissue disorders such as brittle bone disease, cancer and fibrosis. Also, in vitro screening of drug candidates is possible reducing the necessity of animal testing. Downloadfactsheet (PDF, 289 KB)
List of technologies
A long non-coding RNA as a potent and specific cell death effector of cancer cells death effector of cancer cells
The long non-coding RNA (lncRNA) let-A from the fruit fly Drosophila melanogaster provides a template for a novel class of cancer treatments. lncRNA let-A induces rapid cell death in various human cancer cell types and human tumor organoids. Downloadfactsheet (PDF, 350 KB)
Injectable hydrogels for minimally invasive operations
A sponge-like hydrogel fits through a cannula that is a fraction of its volume. This minimally invasive injection procedure is applicable in tissue engineering, regenerative medicine, or drug delivery. Also, this hydrogel-based platform allows the administration of soft robots that operate inside the human body. Downloadfactsheet (PDF, 481 KB), interview with inventors
Microfluidic device for quantitative single cell proteomics
This microfluidic device traps single cells and performs sample preparation for proteomic analysis. The combination of multiple units enables the processes of cell injection, capture, lysis and detection to be completed on a single microfluidic device.
Downloadfactsheet (PDF, 273 KB)
Zero-power event detection for waking up smart devices
This zero-power sensor transforms vibrations into electric signals. It activates smart devices which have been switched off completely using the energy of the trigger event. Smart devices with zero-power sensors, thus, save energy in their dormant state while remaining ready for relevant triggers.
Downloadfactsheet (PDF, 517 KB)
Paper-based electrodes for more accurate rapid tests
This rapid diagnostic test kit combines the convenience of a fluidic assay with the reliability of an electrochemical readout within the same unit. Applications lie in the field of clinical diagnostics, chemical analysis, food inspection and environmental monitoring.
Downloadfactsheet (PDF, 454 KB), external pageYouTube
A bio-orthogonal chemical reaction for manufacturing protein-drug conjugates
- modifies diverse clinically relevant proteins
- in vivo synthesis
- Downloadfactsheet (PDF, 382 KB), video (external pageYouTube)
Instrument for the simultaneous characterization of aerosol particle size and charge distributions
- application for the characterization of medical nebulizers, cough aerosols, filtration masks, e-cigarettes
- real-time measurements (<1 second)
- Downloadfactsheet (PDF, 414 KB)
Recyclable anticorrosion coating for metals with self-healing properties
- intrinsic self-healing & UV-triggered fluorescence
- compatibility with common polymer additives (i.e. pigments)
- tailored glass transition temperature and rheologic properties
- standard thermoplastic processing
- Downloadfactsheet (PDF, 312 KB); video (external pageyoutube)
Upgrading DRAM modules for the protection against Rowhammer attacks
- low hardware cost
- overhead: < 3% power, < 4% area
- seamless integration into current and future DRAM technologies
- Downloadfactsheet (PDF, 912 KB), interview with inventors
Rotational optical delay line assembly for rapid FT-IR spectroscopy
- monitoring subsecond industry processes
- large optical bandwidth, small space requirements
- Downloadfactsheet (PDF, 442 KB)
Low leakage integrated circuits for Internet-of-Things
- reduced power consumption improves battery lifetime
- memristor-transistor technology
- hysteresis-free and convenient for CMOS integration
- Downloadfactsheet (PDF, 267 KB)
Integration of combined total pressure and flow sensor for monitoring and control of blood pumps
- real-time monitoring of blood pressure
- seamless integration in cannula walls
- Downloadfactsheet (PDF, 623 KB)
- interview with inventors (external pageYouTube)
Fully implantable ECG system to measure left ventricular volume
- input for the physiological control of blood pumps
- no signal distortions due to the movement of the patient's body
- Downloadfactsheet (PDF, 647 KB)
- interview with inventors (external pageYouTube)
Smooth interface diaphragms for non-disruptive monitoring of blood flow
- seamless sensor integration
- long-term stable measurement results
- Downloadfactsheet (PDF, 339 KB)
- interview with inventor (external pageYouTube)
Multi-mode physiological controller for blood pumps based on implanted pressure sensors
- adjusts blood flow to patient's needs
- flexible presure sensor positioning
- Downloadfactsheet (PDF, 742 KB)
- interview with inventors (external pageYouTube)
Physiological control of blood pumps based on active intracardiac volume measurements
- adjusts blood output to the patient's need
- relates heart volume to required pump speed
- Downloadfactsheet (PDF, 565 KB)
- interview with inventors (external pageYouTube)
Robust and precise genetic feedback control systems for cell therapy
- autonomous control of therapeutic dose
- reduction of side effects
- robust to interpatient variability (age, sex, disease status)
- Downloadfactsheet (PDF, 438 KB)
Downward ICP mass spectrometer for the analysis of cells and particles
- sample introduction efficiency independent of size and size distribution of the sample aerosol
- simple coupling to cell/particle sorting systems
- Downloadfactsheet (PDF, 517 KB)
Safe and effective Salmonella vaccine for application in livestock rearing
- oral administration, low cost production
- effective against rapidly evolving Salmonella serovars
- interview with inventor (external pageYouTube)
- Downloadfactsheet (PDF, 521 KB)
Expanding, ultrathin, smooth cylinders for implants
- tuneable fixation forces inside a confined vessel
- for trans-catheter heart valve replacement
- interview with inventor (external pageYouTube)
- Downloadfactsheet (PDF, 493 KB)
Nitration of arenes with controllable source of nitronium ions
- late stage functionalization of complex molecules, easy-to-handle, safe, bench-stable
- pharmaceuticals, dyes, explosives, agrochemicals
- interview with inventor (article), Downloadfactsheet (PDF, 514 KB)
3D microfibrillar scaffolds for in vitro cell culture, tissue engineering and surgical applications
- highly porous and aligend 3D scaffold for cell infiltration, easy and fast preparation
- interview with inventor (external pageYouTube)
- Downloadfactsheet (PDF, 389 KB)
PEGylation of therapeutic proteins and peptides
- fast, selective formation of a covalent bond between two large molecules
- chemoselectivity in the presence of unprotected functional groups
- Downloadfactsheet (PDF, 409 KB)
De novo generation of libraries of backbone N-methylated peptides for drug development
- high library complexity due to genetic coding
- promising leads for the development of therapeutic peptides due to their modification
- interview with inventor (article)
- Downloadfactsheet (PDF, 466 KB)
Building blocks for the synthesis of sterochemically pure oligonucleotides
- synthesis of PS oligonucleotide drugs
- stereopure, clinically-validated chemistry
- Downloadfactsheet (PDF, 339 KB)
Real-time user feedback from unpredictable data streams
- application for teleoperation, raytracing, interactive simulations
- surrogate functions provides real-time response
- Downloadfactsheet (PDF, 281 KB)
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